Found 9 matching trials
A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals
PHASE1This will be a single center, open label study comparing baseline character...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers
PHASE1The purpose of this Phase 1 research study is to identify a dose of inhaled...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
PHASE1The purposes of this pilot safety study are to identify a dose of inhaled C...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults
PHASE1The purpose of this study is to determine the range of neutrophil response ...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
Suitability of a Low Dose Lipopolysaccharide (LPS) Inhalation as a Challenge Model
NAThis pilot study is planned to assess the suitability of a low dose Lipopol...
Systemic Inflammatory Response to CCRE
PHASE1Purpose: The purpose of this study is to classify volunteers as endotoxin-r...
Location
Environmental Protection Agency Human Studies facility
Effect of Interleukin-1 Receptor Antagonist on Inhalation of 20,000 EU Clinical Ctr Reference Endotoxin in Normal Volunteers
PHASE1The investigators want to see if healthy people who are given 2 doses of a ...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
Range of Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Otherwise Healthy Smokers
PHASE1Endotoxin is a component of outdoor air pollution, an air contaminant found...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART)
PHASE1To determine the systemic inflammatory effects of inhaled endotoxin and ass...
Location
EPA Human Studies Facility